Article
DNA-array of gene variants in venous leg ulcers: detection of prognostic indicators.
Journal of vascular surgery - 1 Dec 2009
Gemmati Donato, Federici Federica, Catozzi Linda, Gianesini Sergio, Tacconi Giovanna, Scapoli Gian L, Zamboni Paolo
Abstract excerpt
OBJECTIVE: Wound healing in venous leg ulcer (VLU) is a multi-step process involving complex pathways. Scanty knowledge at molecular level hinders clinical assessment and treatment. Anomalous handling of local iron overload, as well as unbalancing in matrix metalloproteinases (MMPs) and transglut...
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