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Article

Distinct loci on chromosome 1q21 and 6q22 predispose to familial nonmedullary thyroid cancer: a SNP array-based linkage analysis of 38 families.

Surgery - 1 Dec 2009

Suh Insoo, Filetti Sebastiano, Vriens Menno R, Guerrero Marlon A, Tumino Salvatore, Wong Mariwil, Shen Wen T, Kebebew Electron, Duh Quan-Yang, Clark Orlo H

Abstract excerpt

BACKGROUND: Familial nonmedullary thyroid cancer (FNMTC) is associated with earlier onset and more aggressive behavior than its sporadic counterpart. Although candidate chromosomal loci have been proposed for isolated families with variants of FNMTC, the etiology of most cases is unknown. We aimed to identify loci linked to FNMTC susceptibility using single-nucleotide polymorphism (SNP) array-based linkage...

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PMID: 19958934
DOI: 10.1016/j.surg.2009.09.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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