Article
The influence of common gene variants of the xenobiotic receptor (PXR) in genetic susceptibility to intrahepatic cholestasis of pregnancy.
Alimentary pharmacology & therapeutics - 1 Mar 2010
Castaño G, Burgueño A, Fernández Gianotti T, Pirola C J, Sookoian S
Abstract excerpt
BACKGROUND: The xenobiotic nuclear pregnane X receptor is implicated in many physiological pathways and diseases, including bile acid detoxification and cholestasis. Aim To estimate the contribution of common gene variants of the xenobiotic receptor (pregnane X receptor, PXR) to genetic susceptib...
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