Article
The fitness effects of random mutations in single-stranded DNA and RNA bacteriophages.
PLoS genetics - 1 Nov 2009
Domingo-Calap Pilar, Cuevas José M, Sanjuán Rafael
Abstract excerpt
Mutational fitness effects can be measured with relatively high accuracy in viruses due to their small genome size, which facilitates full-length sequencing and genetic manipulation. Previous work has shown that animal and plant RNA viruses are very sensitive to mutation. Here, we characterize mu...
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