Article
Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways.
Microbiology and molecular biology reviews : MMBR - 1 Dec 2009
Lo Chien-Chi, Bonner Carol A, Xie Gary, D'Souza Mark, Jensen Roy A
Abstract excerpt
Aspartokinase (Ask) exists within a variable network that supports the synthesis of 9 amino acids and a number of other important metabolites. Lysine, isoleucine, aromatic amino acids, and dipicolinate may arise from the ASK network or from alternative pathways. Ask proteins were subjected to coh...
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