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Article

Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes.

Genome biology - 1 Jan 2002

Copley Shelley D, Dhillon Jasvinder K

Abstract excerpt

BACKGROUND: Glutathione is found primarily in eukaryotes and in Gram-negative bacteria. It has been proposed that eukaryotes acquired the genes for glutathione biosynthesis from the alpha-proteobacterial progenitor of mitochondria. To evaluate this, we have used bioinformatics to analyze sequences of the biosynthetic enzymes gamma-glutamylcysteine ligase and glutathione synthetase. RESULTS: Gamma-glutamylcysteine...

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Identifiers

PMID: 12049666
DOI: 10.1186/gb-2002-3-5-research0025
PMCID: PMC115227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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