Article
Phylogenetic analysis of haloalkane dehalogenases.
Proteins - 1 May 2007
Chovancová Eva, Kosinski Jan, Bujnicki Janusz M, Damborský Jirí
Abstract excerpt
Haloalkane dehalogenases (HLDs) are enzymes that catalyze the cleavage of carbon-halogen bonds by a hydrolytic mechanism. Although comparative biochemical analyses have been published, no classification system has been proposed for HLDs, to date, that reconciles their phylogenetic and functional relationships. In the study presented here, we have analyzed all sequences and structures of genuine HLDs and their...
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