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Article

Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord.

Molecular brain - 28 Nov 2009

Numano Fujiki, Inoue Akihiro, Enomoto Mitsuhiro, Shinomiya Kenichi, Okawa Atsushi, Okabe Shigeo

Abstract excerpt

BACKGROUND: Transplantation of neural stem/progenitor cells is a promising approach toward functional restoration of the damaged neural tissue, but the injured spinal cord has been shown to be an adverse environment for the survival, migration, and differentiation of the donor cells. To improve the efficiency of cell replacement therapy, cell autonomous factors in the donor cells should be optimized. In light of...

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Identifiers

PMID: 19943951
DOI: 10.1186/1756-6606-2-37
PMCID: PMC2789715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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