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Article

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2009

Venstrom Jeffrey M, Zheng Junting, Noor Nabila, Danis Karen E, Yeh Alice W, Cheung Irene Y, Dupont Bo, O'Reilly Richard J, Cheung Nai-Kong V, Hsu Katharine C

Abstract excerpt

PURPOSE: NK cells exhibit cytotoxicity against neuroblastoma. Gene polymorphisms governing NK cell function, therefore, may influence prognosis. Two highly polymorphic genetic loci instrumental in determining NK cell responses encode the NK cell killer immunoglobulin-like receptors (KIR) and their class I human leukocyte antigen (HLA) ligands. We hypothesized that patients with a "missing ligand" KIR-HLA compound...

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Share to Hematopoietic Stem Cell Transplantation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19934297
DOI: 10.1158/1078-0432.CCR-09-1720
PMCID: PMC2788079

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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