Article
Unimpaired trace classical eyeblink conditioning in Purkinje cell degeneration (pcd) mutant mice.
Neurobiology of learning and memory - 1 Mar 2010
Brown Kevin L, Agelan Alexis, Woodruff-Pak Diana S
Abstract excerpt
Young adult Purkinje cell degeneration (pcd) mutant mice, with complete loss of cerebellar cortical Purkinje cells, are impaired in delay eyeblink classical conditioning. In the delay paradigm, the conditioned stimulus (CS) overlaps and coterminates with the unconditioned stimulus (US), and the cerebellar cortex supports normal acquisition. The ability of pcd mutant mice to acquire trace eyeblink conditioning in...
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