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Article

Cerebellar LTD facilitates but is not essential for long-term adaptation of the vestibulo-ocular reflex.

The European journal of neuroscience - 1 Aug 2002

van Alphen A M, De Zeeuw C I

Abstract excerpt

The induction of cerebellar long-term depression (LTD) at the parallel fibre-Purkinje cell synapse is selectively blocked in L7-PKCi transgenic mice, rendering these mice unable to adaptively modify their vestibulo-ocular reflex (VOR) during visuo-vestibular training for a few hours. Despite this deficit, their eye movement performance as well as their general motor behaviour appears unaffected. This combination...

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Identifiers

PMID: 12193192
DOI: 10.1046/j.1460-9568.2002.02094.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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