Article
Iterative pruning PCA improves resolution of highly structured populations.
BMC bioinformatics - 23 Nov 2009
Intarapanich Apichart, Shaw Philip J, Assawamakin Anunchai, Wangkumhang Pongsakorn, Ngamphiw Chumpol, Chaichoompu Kridsadakorn, Piriyapongsa Jittima, Tongsima Sissades
Abstract excerpt
BACKGROUND: Non-random patterns of genetic variation exist among individuals in a population owing to a variety of evolutionary factors. Therefore, populations are structured into genetically distinct subpopulations. As genotypic datasets become ever larger, it is increasingly difficult to correc...
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