Article
Accurate inference of subtle population structure (and other genetic discontinuities) using principal coordinates.
PloS one - 1 Jan 2009
Reeves Patrick A, Richards Christopher M
Abstract excerpt
BACKGROUND: Accurate inference of genetic discontinuities between populations is an essential component of intraspecific biodiversity and evolution studies, as well as associative genetics. The most widely-used methods to infer population structure are model-based, Bayesian MCMC procedures that minimize Hardy-Weinberg and linkage disequilibrium within subpopulations. These methods are useful, but suffer from...
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