Article
Fine-scale subpopulation detection via an SNP-based unsupervised method: A case study on the 1000 Genomes Project resources.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2023
Chaichoompu Kridsadakorn, Wilantho Alisa, Wangkumhang Pongsakorn, Tongsima Sissades, Cavadas Bruno, Pereira Luísa, Van Steen Kristel
Abstract excerpt
SNP-based information is used in several existing clustering methods to detect shared genetic ancestry or to identify population substructure. Here, we present a methodology, called IPCAPS for unsupervised population analysis using iterative pruning. Our method, which can capture fine-level structure in populations, supports ordinal data, and thus can readily be applied to SNP data. Although haplotypes may be...
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