Article
Identification of single-base mismatches in duplex DNA by EPR spectroscopy.
Journal of the American Chemical Society - 23 Dec 2009
Cekan Pavol, Sigurdsson Snorri Th
Abstract excerpt
The spin-labeled nucleoside (T)C, containing 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) conjugated to the exocyclic amino group of C, was used to detect single-base mismatches in duplex DNA for the first time by electron paramagnetic resonance (EPR) spectroscopy. Furthermore, the EPR spectra of...
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