Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2010

Watanabe Yumiko, Metoki Hirohito, Ohkubo Takayoshi, Katsuya Tomohiro, Tabara Yasuharu, Kikuya Masahiro, Hirose Takuo, Sugimoto Ken, Asayama Kei, Inoue Ryusuke, Hara Azusa, Obara Taku, Nakura Jun, Kohara Katsuhiko, Totsune Kazuhito, Ogihara Toshio, Rakugi Hiromi, Miki Tetsuro, Imai Yutaka

Abstract excerpt

Hypertension is a complex multi-factorial and polygenic disorder. Nevertheless, most studies have focused on single-gene effects. Furthermore, a majority of these studies have been cross-sectional and diagnosed hypertension using conventional blood pressure (BP) measurements, which are known to b...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Calcium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calmodulin-Binding Proteins

Share to Follow-Up Studies

Share to Hypertension

Share to Longitudinal Studies

Share to Polymorphism, Single Nucleotide

Share to RGS Proteins

Source

Identifiers

PMID: 19927152
DOI: 10.1038/hr.2009.193

Genes

ADD1
CAT
RGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19927152-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study.PMID 19927152Read ↗

Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population.Semantic proximity Read ↗

Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study.Semantic proximity Read ↗

Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan.Semantic proximity Read ↗

Associations of Variants in the CACNA1A and CACNA1C Genes With Longitudinal Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.Semantic proximity Read ↗

Physical, behavioural and genetic predictors of adult hypertension: the findings of the Kaunas Cardiovascular Risk Cohort study.Semantic proximity Read ↗

Association of Established Blood Pressure Loci With 10-Year Change in Blood Pressure and Their Ability to Predict Incident Hypertension.Semantic proximity Read ↗

The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension-vascular, renal, and cognitive diseases.Semantic proximity Read ↗

A comprehensive evaluation of association between homocysteine levels and single nucleotide polymorphisms with hypertension risk: A protocol of systematic review and network meta-analysis.Semantic proximity Read ↗

alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study.Semantic proximity Read ↗

Aldehyde Dehydrogenase Polymorphisms and Blood Pressure Elevation in the Japanese: A Cross-Sectional and a Longitudinal Study over 20 Years in the Shimane CoHRE Study.Semantic proximity Read ↗

Genetic predisposition to high blood pressure and out-of-office hypertension: Insights from a population sample in liechtenstein.Semantic proximity Read ↗

Association of alpha-ADD1 Gene and Hypertension Risk: A Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.