Article
Genetic mapping of pharmacogenetic regulatory variation.
Current pharmaceutical design - 1 Jan 2009
Raby Benjamin A
Abstract excerpt
The availability of high-throughput genotyping and sequencing platforms has largely removed technological barriers in the mapping the genetic determinants of drug response in human populations, and the set of validated pharmacogenetic variants is gradually increasing. Like the search for disease-susceptibility variation, however, many of the loci identified to date represent the relatively low-hanging fruit with...
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