Article
Association of rare MSH6 variants with familial breast cancer.
Breast cancer research and treatment - 1 Sept 2010
Wasielewski Marijke, Riaz Muhammad, Vermeulen Joyce, van den Ouweland Ans, Labrijn-Marks Ineke, Olmer Renske, van der Spaa Linda, Klijn Jan G M, Meijers-Heijboer Hanne, Dooijes Dennis, Schutte Mieke
Abstract excerpt
Germline mutations in the mismatch repair genes MLH1, MSH2, MSH6, and PMS2 predispose to Lynch syndrome (also known as hereditary non-polyposis colorectal cancer). Recently, we have shown that the CHEK2 1100delC mutation also is associated with Lynch syndrome/Lynch syndrome-associated families al...
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