Article
CHEK2 1100delC and male breast cancer in the Netherlands.
Breast cancer research and treatment - 1 Jul 2009
Wasielewski Marijke, den Bakker Michael A, van den Ouweland Ans, Meijer-van Gelder Marion E, Portengen Henk, Klijn Jan G M, Meijers-Heijboer Hanne, Foekens John A, Schutte Mieke
Abstract excerpt
Mutations in the breast cancer susceptibility genes BRCA1, BRCA2, and CHEK2 are known risk factors for female breast cancer. Mutations in BRCA1 and BRCA2 also are associated with male breast cancer (MBC). Similarly, it had been suggested in the original CHEK2 identification report that the CHEK2 1100delC mutation confers an increased risk for MBC. Here, we have evaluated the risk of CHEK2 1100delC for MBC by...
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