Article
Pre- and postvaccination clonal compositions of invasive pneumococcal serotypes for isolates collected in the United States in 1999, 2001, and 2002.
Journal of clinical microbiology - 1 Mar 2006
Beall Bernard, McEllistrem M Catherine, Gertz Robert E, Wedel Stephanie, Boxrud David J, Gonzalez Antonio L, Medina Marie-Jo, Pai Rekha, Thompson Terry A, Harrison Lee H, McGee Lesley, Whitney Cynthia G
Abstract excerpt
Monitoring of serotypes and their clonal associations is critical as pneumococci adapt to the selective pressures exerted by the pneumococcal seven-valent conjugate vaccine (PCV7). We genotyped 1,476 invasive isolates from the Active Bacterial Core surveillance (705 [89.8%] of the isolates were obtained from children <5 years of age, and 771 [18.4%] of the isolates were obtained from individuals >5 years of age)...
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