Article
Transplanted suprachiasmatic nucleus determines circadian period.
Science (New York, N.Y.) - 23 Feb 1990
Ralph M R, Foster R G, Davis F C, Menaker M
Abstract excerpt
The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was tested by neural transplantation by using a mutant strain of hamster that shows a short circadian period. Small neural grafts from the suprachiasmatic region restored circadian rhythms to arrhythmic animals whose own nucleus had been ablated. The restored rhythms always exhibited the period of the donor genotype regardless of...
Topics
- Animals
- Circadian Rhythm
- Cricetinae
- Immunohistochemistry
- Male
- Mutation
- Nerve Tissue
- Neuropeptide Y
- Suprachiasmatic Nucleus
- Vasopressins