Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Method for Screening Compounds That Influence Virulence Gene Expression in Staphylococcus aureus

17 Nov 2009

Abstract excerpt

We present a simple assay to examine effects of compounds on virulence gene expression in the human pathogen Staphylococcus aureus. The assay employs transcriptional reporter strains carrying lacZ fused to central virulence genes. Compounds affecting virulence gene expression and activity of the agr locus are scored based on color change in the presence of a chromogenic beta-galactosidase substrate. The assay can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial biofilms and quorum sensing
Share to Microbial Metabolism and Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19917763
DOI: 10.1128/aac.00940-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Method for Screening Compounds That Influence Virulence Gene Expression in Staphylococcus aureusPMID 19917763Read ↗

Therapeutic Targeting of the Staphylococcus aureus Accessory Gene Regulator (agr) SystemSemantic proximity Read ↗

Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureusSemantic proximity Read ↗

Virulence Gene Expression of Staphylococcus aureus in Human SkinSemantic proximity Read ↗

Tools, strains, and strategies to effectively conduct anaerobic and aerobic transcriptional reporter screens and assays in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Novel Inhibitors of Staphylococcus aureus Virulence Gene Expression and Biofilm FormationSemantic proximity Read ↗

Exploring Staphylococcus aureus Virulence Factors; Special Emphasis on StaphyloxanthinSemantic proximity Read ↗

Staphylococcus aureus Strain Newman D2C Contains Mutations in Major Regulatory Pathways That Cripple Its Pathogenesis.Semantic proximity Read ↗

Drug-like Fragments Inhibit <i>agr-</i> Mediated Virulence Expression in <i>Staphylococcus</i> aureusSemantic proximity Read ↗

Critical Assessment of the Prospects of Quorum-Quenching Therapy for Staphylococcus aureus InfectionSemantic proximity Read ↗

Staphylococcal Virulence Factors on the Skin of Atopic Dermatitis PatientsSemantic proximity Read ↗

Targeting Virulence in Staphylococcus aureus by Chemical Inhibition of the Accessory Gene Regulator System In VivoSemantic proximity Read ↗

Large-Scale Identification of Genes Required for Full Virulence ofStaphylococcus aureusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.