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Article

Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc.

PloS one - 13 Nov 2009

Lin Chin-Hsing, Lin Chenwei, Tanaka Hisashi, Fero Matthew L, Eisenman Robert N

Abstract excerpt

BACKGROUND: The Myc oncoprotein, a transcriptional regulator involved in the etiology of many different tumor types, has been demonstrated to play an important role in the functions of embryonic stem (ES) cells. Nonetheless, it is still unclear as to whether Myc has unique target and functions in ES cells. METHODOLOGY/PRINCIPAL FINDINGS: To elucidate the role of c-Myc in murine ES cells, we mapped its genomic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19915707
DOI: 10.1371/journal.pone.0007839
PMCID: PMC2773118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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