Article
The clinical implications of MMP-11 and CK-20 expression in human breast cancer.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2010
Cheng Chun-Wen, Yu Jyh-Cherng, Wang Hsiao-Wei, Huang Chiun-Sheng, Shieh Jia-Ching, Fu Yi-Ping, Chang Chia-Wei, Wu Pei-Ei, Shen Chen-Yang
Abstract excerpt
BACKGROUND: Tumor invasiveness and metastasis in cancer progression is manifested by epigenetic abnormality. However, it remains unknown whether transcription regulation of matrix metalloproteinase-11(MMP-11) and cytoskeleton-20 (CK-20) genes for the homoeostasis of epithelial/connective interface that can enhance cell dissemination and invasion may act as alternative mutators to tumor clinicopathology. METHODS:...
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