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Article

Model-based quality assessment and base-calling for second-generation sequencing data.

Biometrics - 1 Sept 2010

Bravo Héctor Corrada, Irizarry Rafael A

Abstract excerpt

Second-generation sequencing (sec-gen) technology can sequence millions of short fragments of DNA in parallel, making it capable of assembling complex genomes for a small fraction of the price and time of previous technologies. In fact, a recently formed international consortium, the 1000 Genomes Project, plans to fully sequence the genomes of approximately 1200 people. The prospect of comparative analysis at the...

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Identifiers

PMID: 19912177
DOI: 10.1111/j.1541-0420.2009.01353.x
PMCID: PMC2888717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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