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Reduced Effectiveness of Oseltamivir in Children Infected With Oseltamivir-resistant Influenza A (H1N1) Viruses With His275Tyr Mutation

4 May 2010

Abstract excerpt

BACKGROUND: Little is known about whether neuraminidase inhibitors are effective for children infected with oseltamivir-resistant influenza A(H1N1) viruses. METHODS: Children aged 15 years and younger having influenza-like illness and who visited outpatient clinics within 48 hours of fever onset were enrolled from 2006-2007 to 2008-2009 influenza seasons in Japan. Patients received oseltamivir, zanamivir, or no...

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PMID: 20442686
DOI: 10.1097/inf.0b013e3181de9d24

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