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Article

Clinical effectiveness of oseltamivir for influenza A(H1N1) virus with H274Y neuraminidase mutation.

The Journal of infection - 1 Sept 2009

Kawai Naoki, Ikematsu Hideyuki, Iwaki Norio, Kondou Kunio, Hirotsu Nobuo, Kawashima Takashi, Maeda Tetsunari, Tanaka Osame, Doniwa Ken-Ichi, Kashiwagi Seizaburo

Abstract excerpt

OBJECTIVE: To evaluate the clinical effectiveness of oseltamivir therapy started within 48h of the onset for influenza A(H1N1) virus with H274Y neuraminidase (NA) mutation. METHODS: Virus was isolated before and four to six days after starting oseltamivir treatment from 73 outpatients with influenza A(H1N1) virus in the 2007-2008 and 2008-2009 seasons. NA inhibition assays (IC(50)) and sequence analyses were done...

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Identifiers

PMID: 19619898
DOI: 10.1016/j.jinf.2009.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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