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Detection and management of antiviral resistance for influenza viruses

1 Nov 2013

Abstract excerpt

Neuraminidase inhibitors (NAIs) are first-line agents for the treatment and prevention of influenza virus infections. As for other antivirals, the development of resistance to NAIs has become an important concern particularly in the case of A(H1N1) viruses and oseltamivir. The most frequently reported change conferring oseltamivir resistance in that viral context is the H275Y neuraminidase mutation (N1...

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PMID: 24215378
DOI: 10.1111/irv.12176

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