Article
Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.
Obesity (Silver Spring, Md.) - 1 Jun 2010
Haupt Axel, Thamer Claus, Heni Martin, Machicao Fausto, Machann Jürgen, Schick Fritz, Stefan Norbert, Fritsche Andreas, Häring Hans-Ulrich, Staiger Harald
Abstract excerpt
A recent meta-analysis of genome-wide association studies has identified six new risk-loci for common obesity. We studied whether these risk loci influence the distribution of body fat depots. We genotyped 1,469 nondiabetic subjects for the single-nucleotide polymorphisms (SNPs) TMEM18 rs6548238, KCTD15 rs11084753, GNPDA2 rs10938397, SH2B1 rs7498665, MTCH2 rs10838738, and NEGR1 . We assessed BMI, waist...
