Article
Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.
The American journal of clinical nutrition - 1 Oct 2009
Bauer Florianne, Elbers Clara C, Adan Roger Ah, Loos Ruth Jf, Onland-Moret N Charlotte, Grobbee Diederick E, van Vliet-Ostaptchouk Jana V, Wijmenga Cisca, van der Schouw Yvonne T
Abstract excerpt
BACKGROUND: New genetic loci, most of which are expressed in the brain, have recently been reported to contribute to the development of obesity. The brain, especially the hypothalamus, is strongly involved in regulating weight and food intake. OBJECTIVES: We investigated whether the recently reported obesity loci are associated with measures of abdominal adiposity and whether these variants affect dietary energy...
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