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Article

Disassembly of Escherichia coli RecA E38K/DeltaC17 nucleoprotein filaments is required to complete DNA strand exchange.

The Journal of biological chemistry - 29 Jan 2010

Britt Rachel L, Haruta Nami, Lusetti Shelley L, Chitteni-Pattu Sindhu, Inman Ross B, Cox Michael M

Abstract excerpt

Disassembly of RecA protein subunits from a RecA filament has long been known to occur during DNA strand exchange, although its importance to this process has been controversial. An Escherichia coli RecA E38K/DeltaC17 double mutant protein displays a unique and pH-dependent mutational separation of DNA pairing and extended DNA strand exchange. Single strand DNA-dependent ATP hydrolysis is catalyzed by this mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19910465
DOI: 10.1074/jbc.M109.028951
PMCID: PMC2823460

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Disassembly of Escherichia coli RecA E38K/DeltaC17 nucleoprotein filaments is required to complete DNA strand exchange.PMID 19910465Read ↗

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