Article
Specific defects in double-stranded DNA unwinding and homologous pairing of a mutant RecA protein.
FEBS letters - 14 Jul 2000
Kurumizaka H, Aihara H, Ikawa S, Shibata T
Abstract excerpt
The DNA molecules bound to RecA filaments are extended 1.5-fold relative to B-form DNA. This extended DNA structure may be important in the recognition of homology between single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). In this study, we show that the K286N mutation specifically impa...
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