Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RecA protein dynamics in the interior of RecA nucleoprotein filaments.

Journal of molecular biology - 12 Apr 1996

Shan Q, Cox M M

Abstract excerpt

We characterize aspects of the conformation and dynamic state of RecA filaments when bound to dsDNA that are specifically linked to the presence of the second of the two bound DNA strands. Filaments bound to dsDNA exhibit a facile exchange between free and bound RecA monomers or oligomers in the filament interior that is not seen on ssDNA. The RecA mutant K72R, which binds but does not hydrolyze ATP, forms mixed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to DNA
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Single-Stranded

Share to Models, Genetic

Share to Mutation

Share to Protein Binding

Share to Recombination, Genetic

Source

Identifiers

PMID: 8636980
DOI: 10.1006/jmbi.1996.0200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RecA protein dynamics in the interior of RecA nucleoprotein filaments.PMID 8636980Read ↗

RecA filament dynamics during DNA strand exchange reactions.Semantic proximity Read ↗

A novel property of the RecA nucleoprotein filament: activation of double- stranded DNA for strand exchange in trans.Semantic proximity Read ↗

Disassembly of Escherichia coli RecA E38K/DeltaC17 nucleoprotein filaments is required to complete DNA strand exchange.Semantic proximity Read ↗

The C terminus of the Escherichia coli RecA protein modulates the DNA binding competition with single-stranded DNA-binding protein.Semantic proximity Read ↗

Mutations in the N-terminal region of RecA that disrupt the stability of free protein oligomers but not RecA-DNA complexes.Semantic proximity Read ↗

Specific defects in double-stranded DNA unwinding and homologous pairing of a mutant RecA protein.Semantic proximity Read ↗

Characterization of RecA1332 in vivo and in vitro. A role for alpha-helix E as a liaison between the subunit-subunit interface and the DNA and ATP binding domains of RecA protein.Semantic proximity Read ↗

Phe217 regulates the transfer of allosteric information across the subunit interface of the RecA protein filament.Semantic proximity Read ↗

Molecular design and functional organization of the RecA protein.Semantic proximity Read ↗

The mutant RecA proteins, RecAR243Q and RecAK245N, exhibit defective DNA binding in homologous pairing.Semantic proximity Read ↗

An archaeal RadA paralog influences presynaptic filament formation.Semantic proximity Read ↗

Dynamic formation of RecA filaments at DNA double strand break repair centers in live cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.