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Article

The effects of telomerase inhibition on prostate tumor‐initiating cells

24 Feb 2010

Abstract excerpt

Prostate cancer is the most common malignancy in men, and patients with metastatic disease have poor outcome even with the most advanced therapeutic approaches. Most cancer therapies target the bulk tumor cells, but may leave intact a small population of tumor-initiating cells (TICs), which are believed to be responsible for the subsequent relapse and metastasis. Using specific surface markers (CD44, integrin...

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PMID: 19908230
DOI: 10.1002/ijc.25043

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