Article
Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer
2022-12-31
Abstract excerpt
Prostate Cancer (PCa) bone metastases are associated with spinal cord compression, fracture, bone pain and death. Despite advances in the medical therapy for localized disease, metastatic disease is incurable and osseous progression is largely dictated by tumor-stromal interactions in the bone microenvironment. We showed previously that tumor bone neutrophils are tumoricidal to PCa but lose their cytotoxic potenti...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 10b1d3d0-74ce-5670-9ed4-b9f4614737d1
- DOI
- 10.1101/2022.12.30.522329