Article
Inhibition of telomerase potentiates enzalutamide efficiency of androgen-sensitive human prostate cancer cells.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Gecgel Karaca Kaan, Muduroglu Mustafa, Erdogan Suat
Abstract excerpt
PURPOSE: Androgen deprivation therapy (ADT) is one of the main strategies to treat prostate cancer (PCa) at various stages of its development. Androgen receptor (AR) antagonists such as enzalutamide are mainstay treatments for castration-sensitive prostate cancer. Though, a majority of patients initially respond to ADT, most will eventually progress to castrate-resistant, due to the development of different...
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