Article
Role of ADRB2 gene polymorphism in asthma and response to beta(2)-agonists in Polish children.
Journal of applied genetics - 1 Jan 2009
Szczepankiewicz A, Breborowicz A, Sobkowiak P, Kramer L, Popiel A
Abstract excerpt
The aims of this study were: (1) to find associations of asthma with single-nucleotide polymorphisms (SNPs) within the ADRB2 gene: Arg16Gly, Gln27Glu, -1023 G/A, -367 T/C, -47 C/T ; (2) to define linkage disequilibrium in the gene region, basing on the analyzed SNPs; and (3) to analyze the importance of ADRB2 polymorphism for response to bronchodilator drugs in children diagnosed with bronchial asthma. We...
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