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Article

Pathology affects different organs in two mouse strains chronically infected by a Trypanosoma cruzi clone: a model for genetic studies of Chagas' disease.

Infection and immunity - 1 Apr 2004

Marinho Claudio R F, Bucci Daniella Z, Dagli Maria Lúcia Z, Bastos Karina R B, Grisotto Marcos G, Sardinha Luiz R, Baptista Cristiane R G M, Gonçalves Carlos Penha, Lima Maria Regina D'Império, Alvarez José M

Abstract excerpt

Chagas' disease is a chronic infection caused by Trypanosoma cruzi and represents an important public health burden in Latin America. Frequently the disease evolves undetectable for decades, while in a significant fraction of the affected individuals it culminates in death by heart failure. Here, we describe a novel murine model of the chronic infection with T. cruzi using a stable clone isolated from a human...

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Identifiers

PMID: 15039360
DOI: 10.1128/IAI.72.4.2350-2357.2004
PMCID: PMC375186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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