Article
YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity.
The Journal of biological chemistry - 1 Jan 2010
Rao Feng, See Rui Yin, Zhang Dongwei, Toh Delon Chengxu, Ji Qiang, Liang Zhao-Xun
Abstract excerpt
The cyclic dinucleotide c-di-AMP [corrected] synthesized by the diadenylate cyclase domain was discovered recently [corrected] as a messenger molecule for signaling DNA breaks in Bacillus subtilis. By searching bacterial genomes, we identified a family of DHH/DHHA1 domain proteins (COG3387) that co-occur with a subset of the diadenylate cyclase domain proteins. Here we report that the B. subtilis protein YybT, a...
Topics
- Acids
- Adenosine Triphosphatases
- Adenosine Triphosphate
- Amino Acid Sequence
- Bacillus subtilis
- Bacterial Proteins
- DNA Damage
- Dinucleoside Phosphates
- Guanosine Tetraphosphate
- Hydrogen-Ion Concentration
- Hydrolysis
- Metals
- Molecular Sequence Data