Article
Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour.
Neuroscience and biobehavioral reviews - 1 Jan 2007
O'Tuathaigh Colm M P, Babovic Daniela, O'Meara Gillian, Clifford Jeremiah J, Croke David T, Waddington John L
Abstract excerpt
A wealth of evidence indicates that schizophrenia is heritable. However, the genetic mechanisms involved are poorly understood. Furthermore, it may be that genes conferring susceptibility interact with one another and with non-genetic factors to modulate risk status and/or the expression of symptoms. Genome-wide scanning and the mapping of several regions linked with risk for schizophrenia have led to the...
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