Homocysteine export from cells cultured in the presence of physiological or superfluous levels of methionine: Methionine loading of non‐transformed, transformed, proliferating, and quiescent cells in culture

Abstract excerpt

Determination of the transient increase in plasma homocysteine following administration of excess methionine is an established procedure for the diagnosis of defects in homocysteine metabolism in patients. This so-called methionine loading test has been used for 25 years, but the knowledge of the response of various cell types to excess methionine is limited. In the present paper we investigated homocysteine...

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