Article
[Association studies of dopamine D4 receptor gene exon 3 in patients with alcohol dependence].
Psychiatria polska - 1 Jan 2000
Grzywacz Anna, Kucharska-Mazur Jolanta, Samochowiec Jerzy
Abstract excerpt
AIM: The aim of this study was to evaluate the role of dopamine D4 receptor (DRD4) exon 3 polymorphisms (48 bp VNTR) in the pathogenesis of alcoholism. This polymorphism was investigated in the association study in a whole group of alcoholics (n = 122) and in homogenous overlapping subgroups: 1) with early age of onset of alcoholism (AOO < or = 26 years) (n = 65) and 2) with a co-occurrence of dissocial...
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