Article
Association of N-acetyltransferases 1 and 2 Polymorphisms with Susceptibility to Head and Neck Cancers-A Meta-Analysis, Meta-Regression, and Trial Sequential Analysis.
Medicina (Kaunas, Lithuania) - 13 Oct 2021
Mohammadi Hady, Roochi Mehrnoush Momeni, Sadeghi Masoud, Garajei Ata, Heidar Hosein, Ghaderi Bayazid, Tadakamadla Jyothi, Meybodi Ali Aghaie, Dallband Mohsen, Mostafavi Sarton, Mostafavi Melina, Salehi Mojtaba, Sadeghi-Bahmani Dena, Brand Serge
Abstract excerpt
Background and objective:N-acetyltransferases 1 and 2 (NAT1 and NAT2) genes have polymorphisms in accordance with slow and rapid acetylator phenotypes with a role in the development of head and neck cancers (HNCs). Herein, we aimed to evaluate the association of NAT1 and NAT2 polymorphisms with susceptibility to HNCs in an updated meta-analysis. Materials and methods: A search was comprehensively performed in...
Topics
- Acetyltransferases
- Arylamine N-Acetyltransferase
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Humans
- Isoenzymes
- Polymorphism, Genetic