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Article

Functional significance of intermediate cleavages in the 3'ETS of the pre-rRNA from Schizosaccharomyces pombe.

Nucleic acids research - 15 Dec 2003

Ivakine Evgueni, Spasov Krasimir, Frendewey David, Nazar Ross N

Abstract excerpt

Pathways for the maturation of ribosomal RNAs are complex with numerous intermediate cleavage sites that are not always conserved closely in the course of evolution. Both in eukaryotes and bacteria genetic analyses and in vitro studies have strongly implicated RNase III-like enzymes in the processing of rRNA precursors. In Schizosacharomyces pombe, for example, the RNase III-like Pac1 nuclease has been shown to...

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Identifiers

PMID: 14654686
DOI: 10.1093/nar/gkg932
PMCID: PMC291872

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Source receipt: pubmed, retrieved 7 Sept 2026.

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