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Article

Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2010

Kurihara Shuichi, Oda Yoshinao, Ohishi Yoshihiro, Kaneki Eisuke, Kobayashi Hiroaki, Wake Norio, Tsuneyoshi Masazumi

Abstract excerpt

Aberrant activation of the Wnt signaling pathway has been implicated in tumorigenesis of a wide range of tumors, including colorectal cancer. Regarding endometrial stromal tumors and related high-grade sarcomas, there have been some reports regarding nuclear accumulation of beta-catenin. To clarify the function of the aberrant Wnt signaling pathway in these tumors, we searched for mutations of the CTNNB1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19898427
DOI: 10.1038/modpathol.2009.162

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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