Article
The aromatic ring of phenylalanine 334 is essential for oligomerization of Vibrio vulnificus hemolysin.
Journal of bacteriology - 1 Jan 2010
Kashimoto Takashige, Ueno Shunji, Koga Takeshi, Fukudome Shinji, Ehara Hayato, Komai Mayumi, Sugiyama Hiroyuki, Susa Nobuyuki
Abstract excerpt
Vibrio vulnificus hemolysin (VVH) is thought to be a member of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins. To date, the structure-function relationships of CDCs produced by Gram-negative bacteria remain largely unknown. We show here that the aromatic ring of phenylala...
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