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Article

Inactivation of Vibrio vulnificus hemolysin through mutation of the N- or C-terminus of the lectin-like domain.

Toxicon : official journal of the International Society on Toxinology - 1 May 2011

Miyoshi Shin-ichi, Abe Yuki, Senoh Mitsutoshi, Mizuno Tamaki, Maehara Yoko, Nakao Hiroshi

Abstract excerpt

Vibrio vulnificus is an etiological agent causing serious systemic infections in the immunocompromised humans or cultured eels. This species commonly produces a hemolytic toxin consisting of the cytolysin domain and the lectin-like domain. For hemolysis, the lectin-like domain specifically binds to cholesterol in the erythrocyte membrane, and to form a hollow oligomer, the toxin is subsequently assembled on the...

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Identifiers

PMID: 21426913
DOI: 10.1016/j.toxicon.2011.03.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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