Article
Enhanced cerebral ischemic lesions after two-vein occlusion in diabetic rats.
Brain research - 14 Jan 2010
Wajima Daisuke, Nakamura Mitsutoshi, Horiuchi Kaoru, Miyake Hitoshi, Takeshima Yasuhiro, Tamura Kentaro, Motoyama Yasushi, Konishi Noboru, Nakase Hiroyuki
Abstract excerpt
The two-vein occlusion (2VO) model is known to be useful for ischemic penumbra studies in vivo. It was applied here to examine sequential changes of regional cerebral blood flow (CBF) and cerebral venous infarction in normal (Long-Evans Tokushima Otsuka, LETO) and diabetic (Otsuka Long-Evans Tokushima Fatty, OLETF) rats. The aim of our study was to examine and compare the ischemic pathogenesis related to regional...
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