Article
Increased behavioral and histological variability arising from changes in cerebrovascular anatomy of the Mongolian gerbil.
Current neurovascular research - 1 Dec 2005
Laidley David T, Colbourne Frederick, Corbett Dale
Abstract excerpt
The Mongolian gerbil (Meriones unguiculatus) has been used extensively as a model of forebrain ischemia. Its unique susceptibility to ischemia was suggested to be due to an incomplete circle of Willis. The relative ease to which ischemia can be induced combined with highly reproducible delayed CA1 cell death following a 5 min occlusion made the model popular in neuroprotection studies. Presently, this assumption...
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