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Article

Loss of PINK1 in medaka fish (Oryzias latipes) causes late-onset decrease in spontaneous movement.

Neuroscience research - 1 Feb 2010

Matsui Hideaki, Taniguchi Yoshihito, Inoue Haruhisa, Kobayashi Yoshito, Sakaki Yoshiyuki, Toyoda Atsushi, Uemura Kengo, Kobayashi Daisuke, Takeda Shunichi, Takahashi Ryosuke

Abstract excerpt

Parkinson's disease is a neurodegenerative disease associated with the degeneration of dopaminergic neurons in the substantia nigra. The PTEN-induced kinase 1 gene (PINK1) is responsible for recessive inherited familial Parkinson's disease (PARK6). Neither the function of PINK1 nor its role in the prevention of Parkinson's disease is fully understood. Gene disruption of PINK1 causes remarkably different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19895857
DOI: 10.1016/j.neures.2009.10.010

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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